منابع مشابه
Chromes from Chromatin: Sonification of the Epigenome
1 The epigenetic modifications are organized in patterns determining the functional properties of the 2 underlying genome. Such patterns, typically measured by ChIP-seq assays of histone modifications, can 3 be combined and translated into musical scores, summarizing multiple signals into a single waveform. 4 As music is recognized as a universal way to convey meaningful information (1), we wan...
متن کاملMetallo-intercalators and metallo-insertors.
Since the elucidation of the structure of double helical DNA, the construction of small molecules that recognize and react at specific DNA sites has been an area of considerable interest. In particular, the study of transition metal complexes that bind DNA with specificity has been a burgeoning field. This growth has been due in large part to the useful properties of metal complexes, which poss...
متن کاملMME ( membrane metallo - endopeptidase )
Location: 3q25.2 Note: Membrane metallo-endopeptidase (MME) is a 100-kD type II transmembrane glycoprotein originally described on human acute lymphoblastic leukemia cell lines and therefore it was originally designated as common acute lymphocytic leukemia antigen (CALLA). MME is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several pept...
متن کاملMetallo-supramolecular cyclic polymers.
Cyclic brush polymers represent an exciting new macromolecular topology. For the first time, this new topology has been combined with metallo-supramolecular interactions to construct novel cyclic brush polymers. Here, ring-expansion metathesis polymerization was used to synthesize a universal cyclic template with a polynorbornene backbone, which was further modified with the metal-chelating syn...
متن کاملCompetition between drum and quasi-planar structures in RhB18-: motifs for metallo-boronanotubes and metallo-borophenes.
Metal-doped boron clusters provide new opportunities to design nanoclusters with interesting structures and bonding. A cobalt-doped boron cluster, CoB18-, has been observed recently to be planar and can be viewed as a motif for metallo-borophenes, whereas the D9d drum isomer as a motif for metallo-boronanotubes is found to be much higher in energy. Hence, whether larger doped boron drums are po...
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ژورنال
عنوان ژورنال: Scientific American
سال: 1891
ISSN: 0036-8733
DOI: 10.1038/scientificamerican01031891-8